SPPL2B anticorps (AA 196-229)
Aperçu rapide pour SPPL2B anticorps (AA 196-229) (ABIN6243975)
Antigène
Voir toutes SPPL2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 196-229
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the Central region of human SPPL2B.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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Autre désignation
- SPPL2B
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Sujet
- Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.
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Poids moléculaire
- 64644
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UniProt
- Q8TCT7
Antigène
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