RIPK3 anticorps

N° du produit ABIN6243991

Cet anticorps anti-RIPK3 est un anticorps Souris Monoclonal détectant RIPK3 dans WB. Adapté pour Humain.

Aperçu rapide pour RIPK3 anticorps (ABIN6243991)

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB)

Clone: 2013CT892-86-49

Détail du produit anti-RIPK3 anticorps

Homologie: H

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3

Sujet: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Poids moléculaire: 56887

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades