ATG10 anticorps (N-Term)

N° du produit ABIN6244154

Détail du produit anti-ATG10 anticorps

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Épitope: AA 15-45, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG10 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.

Clone: RB7550

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ATG10 (ABIN6244154)

Sanchez, Penfornis, Oskowitz, Boonjindasup, Cai, Dhule, Rowan, Kelekar, Krause, Pochampally: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." dans: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).

Détails sur ATG10

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Autre désignation: ATG10 (ATG10 Produits)

Synonymes: anticorps APG10, anticorps APG10L, anticorps pp12616, anticorps Atg10, anticorps ATG10, anticorps MGC123341, anticorps im:7153729, anticorps zgc:123341, anticorps ATATG10, anticorps autophagy 10, anticorps DDBDRAFT_0190076, anticorps DDBDRAFT_0252608, anticorps DDB_0190076, anticorps DDB_0252608, anticorps 5330424L23Rik, anticorps 5430428K15Rik, anticorps AI852123, anticorps Agp10, anticorps Apg10l, anticorps Apg10p, anticorps Atg10l, anticorps autophagy related 10, anticorps autophagy-related 10, anticorps AuTophaGy (yeast Atg homolog), anticorps ATG10 autophagy related 10 homolog (S. cerevisiae), anticorps autophagocytosis-associated family protein, anticorps E2-like conjugating enzyme, anticorps hypothetical protein, anticorps autophagy protein 10, anticorps autophagy-related protein 10, anticorps ATG10, anticorps Atg10, anticorps atg-10, anticorps atg10, anticorps CAALFM_C302930WA, anticorps APG10

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.

Poids moléculaire: 25279

NCBI Accession: NP_001124500, NP_113670

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagy