DKK2 anticorps

N° du produit ABIN6244156

Détail du produit anti-DKK2 anticorps

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DKK2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.

Clone: 1833CT856-7-20

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur DKK2

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Autre désignation: DKK2 (DKK2 Produits)

Synonymes: anticorps DKK-2, anticorps Dkk4, anticorps zgc:171574, anticorps dickkopf WNT signaling pathway inhibitor 2, anticorps DKK2, anticorps Dkk2, anticorps dkk2

Sujet: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Poids moléculaire: 28447

UniProt: Q9UBU2

Pathways: Signalisation WNT