BAFF anticorps

N° du produit ABIN6251872

L’anticorps Souris Monoclonal anti-BAFF a été validé pour FACS et IF. Il convient pour détecter BAFF dans des échantillons de Humain.

Aperçu rapide pour BAFF anticorps (ABIN6251872)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: C257-1638

Détail du produit anti-BAFF anticorps

Purification: Protein G affinity chromatography

Immunogène: Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells

IF: 1-2 μg/mL

Titering of the BAFF antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF

Sujet: BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31  kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

ID gène: 10673

UniProt: Q9Y275

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response