S100A8 anticorps (N-Term)

N° du produit ABIN6251942

Cet anticorps anti-S100A8 est un anticorps Souris Monoclonal détectant S100A8 dans WB. Adapté pour Humain.

Aperçu rapide pour S100A8 anticorps (N-Term) (ABIN6251942)

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A8 est non-conjugé

Application: Western Blotting (WB)

Clone: SA6279

Détail du produit anti-S100A8 anticorps

Épitope: N-Term

Purification: Protein G affinity chromatography

Immunogène: A recombinant protein fragment from the N-terminal region of human S100A8 was used as the immunogen for this antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Western blot: 2-4 μg/mL

Provided assay concentrations are suggestions only, S100A8 antibody titration may be required for optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur S100A8

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Autre désignation: S100A8

Sujet: The S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.

ID gène: 6279

UniProt: P05109

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins