KRT15 anticorps (C-Term)

N° du produit ABIN6252303

Détail du produit anti-KRT15 anticorps

Antigène: KRT15 (Keratin 15 (KRT15))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT15 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Clone: LHK15

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 1-2 μg/mL

WB: 0.5-1 μg/mL

Immunohistochemistry (FFPE & Frozen): 0.5-1 μg/mL for 30 min at RT

Optimal dilution of the Keratin 15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur KRT15

Antigène: KRT15 (Keratin 15 (KRT15))

Autre désignation: Cytokeratin 15 (KRT15 Produits)

Synonymes: anticorps xlk2, anticorps CK15, anticorps K15, anticorps K1CO, anticorps AI528832, anticorps Krt1-15, anticorps Ka15, anticorps wu:fa91c06, anticorps wu:fa95d04, anticorps zgc:55334, anticorps keratin 15, type I L homeolog, anticorps keratin 15, type I, anticorps keratin 15, anticorps krt15.L, anticorps krt15, anticorps KRT15, anticorps Krt15

Sujet: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

ID gène: 3866

UniProt: P19012