MCM7 anticorps (AA 195-319)
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- Antigène Voir toutes MCM7 Anticorps
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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Épitope
- AA 195-319
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MCM7 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogène
- Amino acids 195-319 were used as the immunogen for the MCM7 antibody.
- Clone
- MCM7-1466
- Isotype
- IgG2b
- Top Product
- Discover our top product MCM7 Anticorps primaire
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- Indications d'application
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IF: 0.5-1 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
The stated application concentrations are suggested starting amounts. Titration of the MCM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Antigène
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- Autre désignation
- MCM7 (MCM7 Produits)
- Synonymes
- anticorps CDC47, anticorps MCM2, anticorps P1.1-MCM3, anticorps P1CDC47, anticorps P85MCM, anticorps PNAS146, anticorps MCM7, anticorps AI747533, anticorps Mcmd7, anticorps mCDC47, anticorps chunp6911, anticorps nyz175, anticorps sr:nyz175, anticorps cdc47, anticorps cdc47-2, anticorps mcm7, anticorps xmcm7, anticorps CG4978, anticorps DmMCM7, anticorps DmeMCM7, anticorps Dmel\\CG4978, anticorps McM7, anticorps Mcp-PCR1, anticorps PCR1, anticorps anon-EST:Liang-1.66, anticorps clone 1.66, anticorps minichromosome maintenance complex component 7, anticorps mini-chromosome maintenance complex protein 7, anticorps minichromosome maintenance complex component 2, anticorps minichromosome maintenance complex component 7 L homeolog, anticorps Minichromosome maintenance 7, anticorps minichromosome maintenance complex component 7 S homeolog, anticorps MCM complex subunit Mcm7, anticorps MCM7, anticorps CDC47, anticorps Mcm7, anticorps MCM2, anticorps mcm7, anticorps mcm7.L, anticorps mcm7.S
- Sujet
- Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. [UniProt]
- ID gène
- 4176
- UniProt
- P33993
- Pathways
- Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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