NKIRAS1 anticorps

N° du produit ABIN6252507

Cet anticorps Souris Monoclonal détecte spécifiquement NKIRAS1 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NKIRAS1 anticorps (ABIN6252507)

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKIRAS1 est non-conjugé

Application: Western Blotting (WB)

Clone: NRAS285

Détail du produit anti-NKIRAS1 anticorps

Purification: Protein G purified antibody

Immunogène: A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Western blot: 5-10 μg/mL

Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur NKIRAS1

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Autre désignation: NKIRAS1

Sujet: NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.

NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.

ID gène: 28512

UniProt: Q9NYS0