TXNIP anticorps (N-Term)

N° du produit ABIN6252540

Cet anticorps Lapin Polyclonal détecte spécifiquement TXNIP dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TXNIP anticorps (N-Term) (ABIN6252540)

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNIP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TXNIP anticorps

Épitope: N-Term

Purification: Protein A affinity chromatography

Immunogène: A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1-3 μg/mL

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur TXNIP

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: TXNIP

Sujet: TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.

ID gène: 10628

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome