RSAD2 anticorps (N-Term)

N° du produit ABIN6252810

Cet anticorps Lapin Polyclonal détecte spécifiquement RSAD2 dans WB. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour RSAD2 anticorps (N-Term) (ABIN6252810)

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSAD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RSAD2 anticorps

Épitope: N-Term

Purification: Protein A affinity chromatography purified antibody

Immunogène: A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 3-6 μg/mL

Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur RSAD2

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Autre désignation: Viperin

Sujet: Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).

ID gène: 91543

UniProt: Q8WXG1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response