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Retinoblastoma Protein (Rb) anticorps

Rb Protein Reactivité: Humain, Souris WB, IP, IHC (p) Hôte: Souris Monoclonal RB1-1754 unconjugated
N° du produit ABIN6252811
  • Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Reactivité
    • 173
    • 70
    • 56
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 152
    • 22
    Souris
    Clonalité
    • 150
    • 24
    Monoclonal
    Conjugué
    • 84
    • 17
    • 10
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
    Application
    • 90
    • 89
    • 82
    • 28
    • 25
    • 15
    • 12
    • 9
    • 2
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Protein G affinity chromatography
    Immunogène
    A human recombinant protein was used as the immunogen for this Rb antibody.
    Clone
    RB1-1754
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product Rb Protein Anticorps primaire
  • Indications d'application
    WB: 0.5-1 μg/mL

    IP: 1-2 μg/500 μg protein lysate

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    Titering of the Rb antibody may be required for optimal performance.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Antigène
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Autre désignation
    Retinoblastoma / Rb (Rb Protein Produits)
    Sujet
    Recognizes a 105  kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
    ID gène
    5925
    UniProt
    P06400
    Pathways
    Mitotic G1-G1/S Phases
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