Retinoblastoma Protein (Rb) anticorps
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- Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogène
- A human recombinant protein was used as the immunogen for this Rb antibody.
- Clone
- RB1-1754
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product Rb Protein Anticorps primaire
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- Indications d'application
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WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg protein lysate
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Titering of the Rb antibody may be required for optimal performance. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Antigène
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Autre désignation
- Retinoblastoma / Rb (Rb Protein Produits)
- Sujet
- Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
- ID gène
- 5925
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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