CD40 anticorps

N° du produit ABIN6253105

Cet anticorps anti-CD40 est un anticorps Souris Monoclonal détectant CD40 dans FACS. Adapté pour Humain, Cynomolgus, Babouin et Macaque rhésus.

Aperçu rapide pour CD40 anticorps (ABIN6253105)

Antigène: CD40

Reactivité: Humain, Cynomolgus, Babouin, Macaque rhésus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: G28-5

Détail du produit anti-CD40 anticorps

Fonction: CD40 Unconjugated Antibody

Attributs du produit: The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.

Purification: Purified

Pureté: >95 %

Immunogène: Human tonsillar lymphocytes

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

UniProt: P25942

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints