CD16 anticorps

N° du produit ABIN6253847

Cet anticorps anti-CD16 est un anticorps Souris Monoclonal détectant CD16 dans FACS et ICC. Adapté pour Humain.

Aperçu rapide pour CD16 anticorps (ABIN6253847)

Antigène: CD16

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est non-conjugé

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: B-E16

Détail du produit anti-CD16 anticorps

Specificité: B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]

Pureté: PURE

Isotype: IgG2a

Information d'application

Indications d'application: immunohistochemistry on cytospots,  immunohistochemistry on frozen tissue

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Détails sur CD16

Antigène: CD16

Autre désignation: CD16

Sujet: Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process