CAMK2A anticorps (pThr306)

N° du produit ABIN6254013

L’anticorps Lapin Polyclonal anti-CAMK2A a été validé pour WB et ELISA. Il convient pour détecter CAMK2A dans des échantillons de Rat. Il y a 1 publication disponible.

Aperçu rapide pour CAMK2A anticorps (pThr306) (ABIN6254013)

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CAMK2A anticorps

Épitope: pThr306

Specificité: Specific for endogenous levels of the ~50 kDa α-CaM Kinase II and the ~60 kDa β-CaM Kinase II proteins phosphorylated at Thr306. Immunolabeling is completely eliminated by treatment with λ-phosphatase. It has been reported that this antibody may recognize some level of non-phosphorylated pure recombinant protein, but in our hands (as shown in our WB image) in native tissue, the antibody reacts in a phospho-specific manner.

Réactivité croisée: Souris, Rat

Homologie: bovine, canine, chicken, human, Xenopus, Zebrafish

Attributs du produit: Our CaM Kinase II (Thr306) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects CaM Kinase II (Thr306) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr306 of rat CaMKII, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-CAMK2A (ABIN6254013)

Bhattacharyya, Lee, Muratcioglu, Qiu, Nyayapati, Schulman, Groves, Kuriyan: "Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation." dans: eLife, Vol. 9, (2020) (PubMed).

Détails sur CAMK2A

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Autre désignation: CaM Kinase II

Sujet:

Synonyms: Calcium/calmodulin dependent protein kinase II alpha antibody, Calcium/calmodulin dependent protein kinase II beta antibody, Calcium/calmodulin dependent protein kinase II delta antibody, Calcium/calmodulin dependent protein kinase II gamma antibody, Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody, CaM kinase II alpha antibody, CaM kinase II antibody, CaM kinase II beta antibody, CaM kinase II delta antibody, CaM kinase II gamma antibody, CaM kinase II subunit alpha antibody, CaMK-II subunit alpha antibody, CAMK2 antibody, Camk2a antibody, CAMK2B antibody, CAMK2D antibody, CAMK2G antibody, CAMKA antibody, KCC2A_HUMAN antibody

Description Logic: Our CaM Kinase II (Thr306) rabbit polyclonal phosphospecific primary antibody is produced . It detects CaM Kinase II (Thr306) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: CAMK2A/B

Poids moléculaire: 50 kDa/60 kDa

ID gène: 25400

UniProt: P11310

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction