CD79a anticorps (pTyr182)

N° du produit ABIN6255832

Cet anticorps anti-CD79a Polyclonal Lapin (ABIN6255832) détecte spécifiquement CD79a dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD79a anticorps (pTyr182) (ABIN6255832)

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CD79a anticorps

Épitope: pTyr182

Specificité: Phospho-CD79A (Tyr182) Antibody detects endogenous levels of CD79A.

Réactivité croisée: Humain, Souris

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human CD79A around the phosphorylation site of Tyr182.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79A

Sujet:

Description: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Gene: CD79A

Poids moléculaire: 45-55kDa

ID gène: 973

UniProt: P11912

Pathways: BCR Signaling