Synaptotagmin anticorps (pSer309)

N° du produit ABIN6256263

L’anticorps Lapin Polyclonal anti-Synaptotagmin a été validé pour WB, IHC, ELISA, IF et ICC. Il convient pour détecter Synaptotagmin dans des échantillons de Rat, Souris et Humain.

Aperçu rapide pour Synaptotagmin anticorps (pSer309) (ABIN6256263)

Antigène: Synaptotagmin (SYT)

Reactivité: Rat, Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptotagmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Synaptotagmin anticorps

Épitope: pSer309

Specificité: Phospho-Synaptotagmin (Ser309) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Serine 309

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Serine 309

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Synaptotagmin

Antigène: Synaptotagmin (SYT)

Autre désignation: Synaptotagmin

Sujet:

Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene: SYT1

Poids moléculaire: 47kDa

ID gène: 6857

UniProt: P21579, Q8N9I0