Ephrin B2 anticorps (pTyr330)

N° du produit ABIN6256709

Cet anticorps Lapin Polyclonal détecte spécifiquement Ephrin B2 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Ephrin B2 anticorps (pTyr330) (ABIN6256709)

Antigène: Ephrin B2 (EFNB2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin B2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Ephrin B2 anticorps

Épitope: pTyr330

Specificité: Phospho-Ephrin B2 (Tyr330) Antibody detects endogenous levels of Ephrin B2 only when phosphorylated at Tyrosine 330.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Ephrin B2 around the phosphorylation site of Tyr330.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Ephrin B2

Antigène: Ephrin B2 (EFNB2)

Autre désignation: EFNB2

Sujet:

Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Gene: EFNB2

Poids moléculaire: 37kDa

ID gène: 1948

UniProt: P52799

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation