ARHGAP17 anticorps (Internal Region)

N° du produit ABIN6257043

L’anticorps Lapin Polyclonal anti-ARHGAP17 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter ARHGAP17 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ARHGAP17 anticorps (Internal Region) (ABIN6257043)

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ARHGAP17 anticorps

Épitope: Internal Region

Specificité: RHG17 Antibody detects endogenous levels of total RHG17.

Homologie: Bovine,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RHG17, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARHGAP17

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Autre désignation: ARHGAP17

Sujet:

Description: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Gene: ARHGAP17

Poids moléculaire: 100 kDa

ID gène: 55114

UniProt: Q68EM7