IFNAR2 anticorps (C-Term)

N° du produit ABIN6257230

Détail du produit anti-IFNAR2 anticorps

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: IFNAR2 Antibody detects endogenous levels of total IFNAR2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IFNAR2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur IFNAR2

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Autre désignation: IFNAR2 (IFNAR2 Produits)

Synonymes: anticorps AI747302, anticorps Ifnar-2, anticorps IFN-R, anticorps IFN-alpha-REC, anticorps IFNABR, anticorps IFNARB, anticorps IFN-R-2, anticorps IFNBR, anticorps interferon alpha and beta receptor subunit 2, anticorps interferon (alpha and beta) receptor 2, anticorps IFNAR2, anticorps Ifnar2

Sujet:

Description: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).

Gene: IFNAR2

ID gène: 3455

UniProt: P48551

Pathways: Signalistation JAK/STAT, Hepatitis C