MYST2 anticorps (Internal Region)

N° du produit ABIN6257254

Détail du produit anti-MYST2 anticorps

Antigène: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYST2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MYST2 Antibody detects endogenous levels of total MYST2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MYST2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-MYST2 (ABIN6257254)

Yang, Guan, Shaikh, Liang, Sun, Wang, Li, Qiu, Li: "Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 5, pp. 2159-2169, (2018) (PubMed).

Détails sur MYST2

Antigène: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Autre désignation: KAT7 (MYST2 Produits)

Synonymes: anticorps Myst2, anticorps HBO1, anticorps HBOA, anticorps MYST2, anticorps ZC2HC7, anticorps Hbo1, anticorps Hboa, anticorps lysine acetyltransferase 7, anticorps K(lysine) acetyltransferase 7, anticorps MYST histone acetyltransferase 2, anticorps Kat7, anticorps KAT7, anticorps myst2

Sujet:

Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity). Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067). Specifically represses AR-mediated transcription.

Gene: KAT7

Poids moléculaire: 75 kDa

ID gène: 11143

UniProt: O95251