RAB38 anticorps (Internal Region)

N° du produit ABIN6257448

Détail du produit anti-RAB38 anticorps

Antigène: RAB38 (RAB38, Member RAS Oncogene Family (RAB38))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB38 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: RAB38 Antibody detects endogenous levels of total RAB38.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RAB38, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RAB38

Antigène: RAB38 (RAB38, Member RAS Oncogene Family (RAB38))

Autre désignation: RAB38 (RAB38 Produits)

Synonymes: anticorps RAB38, anticorps rab38, anticorps 2310011F14Rik, anticorps AU043391, anticorps cht, anticorps NY-MEL-1, anticorps rrGTPbp, anticorps R, anticorps Ruby, anticorps RAB38, member RAS oncogene family, anticorps RAB38a, member RAS oncogene family, anticorps RAB38, member RAS oncogene family S homeolog, anticorps RAB38, anticorps rab38a, anticorps rab38.S, anticorps Rab38

Sujet:

Description: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes, the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).

Gene: RAB38

Poids moléculaire: 26 kDa

ID gène: 23682

UniProt: P57729