Apoptosis Inhibitor 5 anticorps (C-Term)

N° du produit ABIN6257683

Cet anticorps anti-Apoptosis Inhibitor 5 est un anticorps Lapin Polyclonal détectant Apoptosis Inhibitor 5 dans WB, ELISA, IHC, IF et ICC. Adapté pour Humain et Souris.

Aperçu rapide pour Apoptosis Inhibitor 5 anticorps (C-Term) (ABIN6257683)

Antigène: Apoptosis Inhibitor 5 (API5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Apoptosis Inhibitor 5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Apoptosis Inhibitor 5 anticorps

Épitope: C-Term

Specificité: API-5 Antibody detects endogenous levels of total API-5.

Homologie: Pig,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human API-5, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Apoptosis Inhibitor 5

Antigène: Apoptosis Inhibitor 5 (API5)

Autre désignation: API5

Sujet:

Description: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Gene: API5

Poids moléculaire: 58 kDa

ID gène: 8539

UniProt: Q9BZZ5

Pathways: Growth Factor Binding