ARHGAP18 anticorps (Internal Region)

N° du produit ABIN6257900

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGAP18 dans WB, ELISA, IHC, IF et ICC. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour ARHGAP18 anticorps (Internal Region) (ABIN6257900)

Antigène: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ARHGAP18 anticorps

Épitope: Internal Region

Specificité: RHG18 Antibody detects endogenous levels of total RHG18.

Homologie: Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RHG18, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARHGAP18

Antigène: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Autre désignation: ARHGAP18

Sujet:

Description: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).

Gene: ARHGAP18

Poids moléculaire: 75 kDa

ID gène: 93663

UniProt: Q8N392