GPR75 anticorps (Internal Region)

N° du produit ABIN6258191

Cet anticorps Lapin Polyclonal détecte spécifiquement GPR75 dans WB, ELISA, IF et ICC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour GPR75 anticorps (Internal Region) (ABIN6258191)

Antigène: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR75 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-GPR75 anticorps

Épitope: Internal Region

Specificité: GPR75 Antibody detects endogenous levels of total GPR75.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GPR75, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GPR75

Antigène: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Autre désignation: GPR75

Sujet:

Description: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Gene: GPR75

Poids moléculaire: 59 kDa

ID gène: 10936

UniProt: O95800