MCF2L anticorps (Internal Region)

N° du produit ABIN6258277

Cet anticorps anti-MCF2L est un anticorps Lapin Polyclonal détectant MCF2L dans WB, ELISA et IHC. Adapté pour Humain et Rat.

Aperçu rapide pour MCF2L anticorps (Internal Region) (ABIN6258277)

Antigène: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCF2L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MCF2L anticorps

Épitope: Internal Region

Specificité: MCF2L Antibody detects endogenous levels of total MCF2L.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCF2L, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MCF2L

Antigène: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Autre désignation: MCF2L

Sujet:

Description: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669).

Gene: MCF2L

ID gène: 23263

UniProt: O15068

Pathways: Neurotrophin Signaling Pathway, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis