POU3F2 anticorps (N-Term)

N° du produit ABIN6258305

Cet anticorps Lapin Polyclonal détecte spécifiquement POU3F2 dans WB, ELISA, IF et ICC. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour POU3F2 anticorps (N-Term) (ABIN6258305)

Antigène: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU3F2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-POU3F2 anticorps

Épitope: N-Term

Specificité: POU3F2 Antibody detects endogenous levels of total POU3F2.

Homologie: Pig,Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human POU3F2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur POU3F2

Antigène: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Autre désignation: POU3F2

Sujet:

Description: Transcription factor that plays a key role in neuronal differentiation (By similarity). Binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a non-conserved spacer region of 0, 2, or 3 nucleotides (By similarity). The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Acts downstream of ASCL1, accessing chromatin that has been opened by ASCL1, and promotes transcription of neuronal genes (By similarity).

Gene: POU3F2

Poids moléculaire: 47 kDa

ID gène: 5454

UniProt: P20265