TCF7 anticorps
Aperçu rapide pour TCF7 anticorps (ABIN6258455)
Antigène
Voir toutes TCF7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- TCF7 Antibody detects endogenous levels of total TCF7
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Réactivité croisée
- Humain, Souris
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide
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Isotype
- IgG
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Indications d'application
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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Autre désignation
- TCF7
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Sujet
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Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Gene: TCF7
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Poids moléculaire
- 42 kDa
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ID gène
- 6932
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UniProt
- P36402
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Pathways
- Signalisation WNT
Antigène
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