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CDC20 anticorps (N-Term)

CDC20 Reactivité: Humain, Souris, Rat WB, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258749
  • Antigène Voir toutes CDC20 Anticorps
    CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
    Épitope
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 56
    • 20
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 14
    Lapin
    Clonalité
    • 42
    • 15
    Polyclonal
    Conjugué
    • 33
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CDC20 est non-conjugé
    Application
    • 35
    • 23
    • 19
    • 12
    • 12
    • 10
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    Specificité
    CDC20 Antibody detects endogenous levels of total CDC20.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CDC20, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CDC20 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
    Autre désignation
    CDC20 (CDC20 Produits)
    Synonymes
    anticorps X-FZY, anticorps ba276h19.3, anticorps cdc20a, anticorps fizzy1, anticorps p55cdc, anticorps CDC20A, anticorps bA276H19.3, anticorps p55CDC, anticorps 2310042N09Rik, anticorps C87100, anticorps cell division cycle 20, anticorps cell division cycle 20 L homeolog, anticorps cell division cycle 20 homolog (S. cerevisiae), anticorps cdc20, anticorps CDC20, anticorps cdc20.L, anticorps Cdc20
    Sujet

    Description: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

    Gene: CDC20

    Poids moléculaire
    50 kDa
    ID gène
    991
    UniProt
    Q12834
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