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RGS7 anticorps (Internal Region)

RGS7 Reactivité: Humain, Souris, Rat WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258913
  • Antigène Voir toutes RGS7 Anticorps
    RGS7 (Regulator of G-Protein Signaling 7 (RGS7))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 42
    • 15
    • 14
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 39
    • 2
    • 1
    Lapin
    Clonalité
    • 42
    Polyclonal
    Conjugué
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RGS7 est non-conjugé
    Application
    • 28
    • 21
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    RGS7 Antibody detects endogenous levels of total RGS7.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human RGS7, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RGS7 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RGS7 (Regulator of G-Protein Signaling 7 (RGS7))
    Autre désignation
    RGS7 (RGS7 Produits)
    Synonymes
    anticorps zgc:92793, anticorps RGS7, anticorps regulator of G-protein signaling 7, anticorps regulator of G protein signaling 7a, anticorps regulator of G protein signaling 7, anticorps Regulator of G protein Signaling, anticorps RGS7, anticorps rgs7a, anticorps CpipJ_CPIJ014798, anticorps Tsp_03415, anticorps rgs-7, anticorps Rgs7
    Sujet

    Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).

    Gene: RGS7

    Poids moléculaire
    65 kDa
    ID gène
    6000
    UniProt
    P49802
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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