IL12RB1 anticorps (Internal Region)

N° du produit ABIN6259088

Cet anticorps Lapin Polyclonal détecte spécifiquement IL12RB1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour IL12RB1 anticorps (Internal Region) (ABIN6259088)

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-IL12RB1 anticorps

Épitope: Internal Region

Specificité: IL12RB1 Antibody detects endogenous levels of total IL12RB1.

Homologie: Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IL12RB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur IL12RB1

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Autre désignation: IL12RB1

Sujet:

Description: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Gene: IL12RB1

Poids moléculaire: 73 kDa

ID gène: 3594

UniProt: P42701

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation