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NK2 Homeobox 5 anticorps (Internal Region)

NKX2-5 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259127
  • Antigène Voir toutes NK2 Homeobox 5 (NKX2-5) Anticorps
    NK2 Homeobox 5 (NKX2-5)
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 40
    • 19
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 42
    • 7
    • 1
    Lapin
    Clonalité
    • 44
    • 6
    Polyclonal
    Conjugué
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp NK2 Homeobox 5 est non-conjugé
    Application
    • 43
    • 29
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Nkx2.5 Antibody detects endogenous levels of total Nkx2.5.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Nkx2.5, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NKX2-5 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    NK2 Homeobox 5 (NKX2-5)
    Autre désignation
    NKX2-5 (NKX2-5 Produits)
    Synonymes
    anticorps CHNG5, anticorps CSX, anticorps CSX1, anticorps HLHS2, anticorps NKX2.5, anticorps NKX2E, anticorps NKX4-1, anticorps VSD3, anticorps Csx, anticorps Nkx-2.5, anticorps Nkx2.5, anticorps tinman, anticorps nk2.5, anticorps nkx2-5, anticorps zgc:111912, anticorps AR2, anticorps XNkx2-5, anticorps csx, anticorps nkx-2.5, anticorps nkx2-5b, anticorps nkx2.5, anticorps NKX2-5, anticorps Nkx2-5, anticorps csx1, anticorps nkx2e, anticorps XNkx-2.5, anticorps CNKX-2.5, anticorps NKX-2.5, anticorps NK2 homeobox 5, anticorps NK2 homeobox 5 S homeolog, anticorps NKX2-5, anticorps Nkx2-5, anticorps nkx2.5, anticorps nkx2-5.S, anticorps nkx2-5
    Sujet

    Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.

    Gene: NKX2-5

    Poids moléculaire
    50 kDa
    ID gène
    1482
    UniProt
    P52952
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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