SF3B4 anticorps (N-Term)

N° du produit ABIN6259186

Détail du produit anti-SF3B4 anticorps

Antigène: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3B4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: SF3B4 Antibody detects endogenous levels of total SF3B4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SF3B4, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SF3B4

Antigène: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Autre désignation: SF3B4 (SF3B4 Produits)

Synonymes: anticorps chunp6902, anticorps fb36a04, anticorps wu:fb36a04, anticorps 49kDa, anticorps SF3b49, anticorps SF3b50, anticorps Sap49, anticorps spx, anticorps AFD1, anticorps Hsh49, anticorps SAP49, anticorps Splicing factor 3B subunit 4, anticorps splicing factor 3b, subunit 4, anticorps splicing factor 3b subunit 4 S homeolog, anticorps splicing factor 3b subunit 4, anticorps sap-49, anticorps sf3b4, anticorps Sf3b4, anticorps sf3b4.S, anticorps SF3B4

Sujet:

Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).

Gene: SF3B4

Poids moléculaire: 55 kDa

ID gène: 10262

UniProt: Q15427