MCF2 anticorps (Internal Region)

N° du produit ABIN6259504

Détail du produit anti-MCF2 anticorps

Antigène: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCF2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: MCF2 Antibody detects endogenous levels of total MCF2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MCF2

Antigène: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Autre désignation: MCF2 (MCF2 Produits)

Synonymes: anticorps ARHGEF21, anticorps DBL, anticorps MCF.2 cell line derived transforming sequence, anticorps MCF2

Sujet:

Description: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.

Gene: MCF2

Poids moléculaire: 108 kDa

ID gène: 4168

UniProt: P10911