CLN5 anticorps (Internal Region)

N° du produit ABIN6259553

Détail du produit anti-CLN5 anticorps

Antigène: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLN5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CLN5 Antibody detects endogenous levels of total CLN5.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CLN5, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CLN5

Antigène: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Autre désignation: CLN5 (CLN5 Produits)

Synonymes: anticorps NCL, anticorps A730075N08Rik, anticorps CLN5, intracellular trafficking protein, anticorps ceroid-lipofuscinosis, neuronal 5, anticorps CLN5, anticorps Cln5

Sujet:

Description: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).

Gene: CLN5

Poids moléculaire: 46 kDa

ID gène: 1203

UniProt: O75503