MYBL1 anticorps (Internal Region)
Aperçu rapide pour MYBL1 anticorps (Internal Region) (ABIN6259660)
Antigène
Voir toutes MYBL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- A-Myb Antibody detects endogenous levels of total A-Myb.
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Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human A-Myb, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- MYBL1 (Myb-Like Protein 1 (MYBL1))
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Autre désignation
- MYBL1
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Sujet
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Description: Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity).
Gene: MYBL1
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Poids moléculaire
- 85kDa
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ID gène
- 4603
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UniProt
- P10243
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Pathways
- Cycle Cellulaire, Chromatin Binding
Antigène
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