MYBL1 anticorps (Internal Region)

N° du produit ABIN6259660

Détail du produit anti-MYBL1 anticorps

Antigène: MYBL1 (Myb-Like Protein 1 (MYBL1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYBL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: A-Myb Antibody detects endogenous levels of total A-Myb.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human A-Myb, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MYBL1

Antigène: MYBL1 (Myb-Like Protein 1 (MYBL1))

Autre désignation: MYBL1 (MYBL1 Produits)

Synonymes: anticorps A-myb, anticorps G1-419-6, anticorps repro9, anticorps AMYB, anticorps xamyb, anticorps A-MYB, anticorps MYBL, anticorps myeloblastosis oncogene-like 1, anticorps MYB proto-oncogene like 1, anticorps MYB proto-oncogene like 1 L homeolog, anticorps Mybl1, anticorps mybl1.L, anticorps MYBL1

Sujet:

Description: Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity).

Gene: MYBL1

Poids moléculaire: 85kDa

ID gène: 4603

UniProt: P10243

Pathways: Cycle Cellulaire, Chromatin Binding