AKR7A2 anticorps (Internal Region)

N° du produit ABIN6259864

Cet anticorps anti-AKR7A2 est un anticorps Lapin Polyclonal détectant AKR7A2 dans WB, IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour AKR7A2 anticorps (Internal Region) (ABIN6259864)

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR7A2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-AKR7A2 anticorps

Épitope: Internal Region

Specificité: AKR7A2 Antibody detects endogenous levels of total AKR7A2.

Homologie: Pig,Bovine,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AKR7A2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AKR7A2

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Autre désignation: AKR7A2

Sujet:

Description: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Gene: AKR7A2

Poids moléculaire: 40kDa

ID gène: 8574

UniProt: O43488