APLF anticorps (Internal Region)

N° du produit ABIN6259979

Cet anticorps Lapin Polyclonal détecte spécifiquement APLF dans ELISA, WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour APLF anticorps (Internal Region) (ABIN6259979)

Antigène: APLF (Aprataxin and PNKP Like Factor (APLF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLF est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-APLF anticorps

Épitope: Internal Region

Specificité: APLF Antibody detects endogenous levels of total APLF.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human APLF, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur APLF

Antigène: APLF (Aprataxin and PNKP Like Factor (APLF))

Autre désignation: APLF

Sujet:

Description: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

Gene: APLF

Poids moléculaire: 57kDa

ID gène: 200558

UniProt: Q8IW19

Pathways: Réparation de l'ADN