ARPP19 anticorps (N-Term)

N° du produit ABIN6260049

L’anticorps Lapin Polyclonal anti-ARPP19 a été validé pour ELISA, IHC et WB. Il convient pour détecter ARPP19 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ARPP19 anticorps (N-Term) (ABIN6260049)

Antigène: ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARPP19 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-ARPP19 anticorps

Épitope: N-Term

Specificité: ARPP19 Antibody detects endogenous levels of total ARPP19.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARPP19, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARPP19

Antigène: ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))

Autre désignation: ARPP19

Sujet:

Description: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.

Gene: ARPP19

Poids moléculaire: 12 kDa

ID gène: 10776

UniProt: P56211

Pathways: Regulation of Carbohydrate Metabolic Process