CABIN1 anticorps (Internal Region)
Aperçu rapide pour CABIN1 anticorps (Internal Region) (ABIN6260386)
Antigène
Voir toutes CABIN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Specificité
- CABIN1 Antibody detects endogenous levels of total CABIN1.
-
Homologie
- Pig,Bovine,Rabbit,Dog
-
Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogène
- A synthesized peptide derived from human CABIN1, corresponding to a region within the internal amino acids.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Date de péremption
- 12 months
-
-
- CABIN1 (Calcineurin Binding Protein 1 (CABIN1))
-
Autre désignation
- CABIN1
-
Sujet
-
Description: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.
Gene: CABIN1
-
Poids moléculaire
- 246kDa
-
ID gène
- 23523
-
UniProt
- Q9Y6J0
Antigène
-