DOCK7 anticorps (N-Term)

N° du produit ABIN6261348

L’anticorps Lapin Polyclonal anti-DOCK7 a été validé pour ELISA et WB. Il convient pour détecter DOCK7 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour DOCK7 anticorps (N-Term) (ABIN6261348)

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK7 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-DOCK7 anticorps

Épitope: N-Term

Specificité: DOCK7 Antibody detects endogenous levels of total DOCK7.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DOCK7

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Autre désignation: DOCK7

Sujet:

Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

Gene: DOCK7

Poids moléculaire: 242kDa

ID gène: 85440

UniProt: Q96N67