EDEM1 anticorps (C-Term)

N° du produit ABIN6261429

Détail du produit anti-EDEM1 anticorps

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDEM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: EDEM1 Antibody detects endogenous levels of total EDEM1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human EDEM1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur EDEM1

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Autre désignation: EDEM1 (EDEM1 Produits)

Synonymes: anticorps zgc:55816, anticorps edem, anticorps EDEM1, anticorps EDEM, anticorps A130059K23Rik, anticorps mKIAA0212, anticorps RGD1563633, anticorps ER degradation enhancer, mannosidase alpha-like 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1, anticorps ER degradation-enhancing alpha-mannosidase-like protein 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1 L homeolog, anticorps edem1, anticorps EDEM1, anticorps LOC100637820, anticorps edem1.L, anticorps Edem1

Sujet:

Description: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

Gene: EDEM1

Poids moléculaire: 74 kDa

ID gène: 9695

UniProt: Q92611

Pathways: ER-Nucleus Signaling