ENOS anticorps (C-Term)

N° du produit ABIN6261536

Cet anticorps Lapin Polyclonal détecte spécifiquement ENOS dans WB, ELISA, IHC, IF et ICC. Il présente une réactivité envers Humain, Rat et Souris et a été mentionné dans 5+ publications.

Aperçu rapide pour ENOS anticorps (C-Term) (ABIN6261536)

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENOS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ENOS anticorps

Épitope: C-Term

Specificité: ENOS Antibody detects endogenous levels of total eNOS.

Homologie: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human eNOS, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-ENOS (ABIN6261536)

Hu, Cheng, Huang, Cai, Lian, Wang, Gao: "Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 42, pp. 245-257, (2018) (PubMed).

Ruan, Ren, Zhang, Zhu, Xu, Wang: "Cardioprotective Effects of QiShenYiQi Dripping Pills on Transverse Aortic Constriction-Induced Heart Failure in Mice." dans: Frontiers in physiology, Vol. 9, pp. 324, (2018) (PubMed).

Zhu, Hu, Lv, Cheng, Gao: "Effects of oligomeric grape seed proanthocyanidins on L-NAME-induced hypertension in pregnant mice: Role of oxidative stress and endothelial dysfunction." dans: Phytotherapy research : PTR, Vol. 32, Issue 9, pp. 1836-1847, (2018) (PubMed).

Li, Wang, Zha, Cao, Sheng, Chen: "SIRT1 inhibits TGF-β-induced endothelial-mesenchymal transition in human endothelial cells with Smad4 deacetylation." dans: Journal of cellular physiology, (2018) (PubMed).

Lu, Wang, Wang, Zhang, Liu, Zhang, Geng, Shan: "Beneficial effects of renal denervation on cardiac angiogenesis in rats with prolonged pressure overload." dans: Acta physiologica (Oxford, England), Vol. 220, Issue 1, pp. 47-57, (2017) (PubMed).

Détails sur ENOS

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Autre désignation: NOS3

Sujet:

Description: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Gene: NOS3

Poids moléculaire: 140kDa

ID gène: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling