Fibronectin 1 anticorps (C-Term)

N° du produit ABIN6261746

Cet anticorps Lapin Polyclonal détecte spécifiquement Fibronectin 1 dans WB, ELISA, IHC, IF et ICC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 2+ publications.

Aperçu rapide pour Fibronectin 1 anticorps (C-Term) (ABIN6261746)

Antigène: Fibronectin 1 (FN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibronectin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Fibronectin 1 anticorps

Épitope: C-Term

Specificité: Fibronectin Antibody detects endogenous levels of total Fibronectin.

Homologie: Pig,Bovine,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Fibronectin, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-Fibronectin 1 (ABIN6261746)

Yang, Zhou, Zhu, Fan, Liu, Duan, Tang, Shou, Zuo: "miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition." dans: Journal of gastroenterology and hepatology, Vol. 32, Issue 12, pp. 1966-1974, (2018) (PubMed).

Xu, Sun, Fang, Song, Yan, Chen, Jiang, Fei, Zhao, Leboeuf, Li, Wang, Janin, Wang, Zhao: "JAM-A overexpression is related to disease progression in diffuse large B-cell lymphoma and downregulated by lenalidomide." dans: Scientific reports, Vol. 7, Issue 1, pp. 7433, (2018) (PubMed).

Détails sur Fibronectin 1

Antigène: Fibronectin 1 (FN1)

Autre désignation: FN1

Sujet:

Description: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

Gene: FN1

Poids moléculaire: 263 kDa

ID gène: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy