GPSM2 anticorps (C-Term)

N° du produit ABIN6262065

L’anticorps Lapin Polyclonal anti-GPSM2 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter GPSM2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GPSM2 anticorps (C-Term) (ABIN6262065)

Antigène: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPSM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-GPSM2 anticorps

Épitope: C-Term

Specificité: GPSM2 Antibody detects endogenous levels of total GPSM2.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GPSM2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GPSM2

Antigène: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Autre désignation: GPSM2

Sujet:

Description: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed:22327364). Plays a role in metaphase spindle orientation (PubMed:22327364). Plays also an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity).

Gene: GPSM2

Poids moléculaire: 77 kDa

ID gène: 29899

UniProt: P81274

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling