HLA-DMA anticorps

N° du produit ABIN6262285

Détail du produit anti-HLA-DMA anticorps

Antigène: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DMA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: HLA-DMA Antibody detects endogenous levels of total HLA-DMA

Réactivité croisée: Humain, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HLA-DMA

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur HLA-DMA

Antigène: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Autre désignation: HLA-DMA (HLA-DMA Produits)

Synonymes: anticorps RT1.Ma, anticorps RT1.DMa, anticorps HLA-DMA, anticorps H-2Ma, anticorps H2-Ma, anticorps D6S222E, anticorps DMA, anticorps HLADM, anticorps RING6, anticorps RT1 class II, locus DMa, anticorps SLA-DM alpha chain, anticorps major histocompatibility complex, class II, DM alpha, anticorps histocompatibility 2, class II, locus DMa, anticorps RT1-DMa, anticorps SLA-DMA, anticorps DLA-DMA, anticorps H2-DMa, anticorps HLA-DMA

Sujet:

Description: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Gene: HLA-DMA

Poids moléculaire: 29 kDa

UniProt: P28067

Pathways: Cancer Immune Checkpoints