ITGA3 anticorps (Internal Region)

N° du produit ABIN6262608

L’anticorps anti-ITGA3 Polyclonal Lapin est utilisé pour la détection de ITGA3 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, IHC, ICC et IF.

Aperçu rapide pour ITGA3 anticorps (Internal Region) (ABIN6262608)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-ITGA3 anticorps

Épitope: Internal Region

Fonction: Integrin alpha 3 Antibody

Specificité: Integrin α3 (CD49c) Antibody detects endogenous levels of total Integrin α3 (CD49c)

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Integrin alpha 3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: Integrin alpha 3

Sujet:

Description: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Gene: ITGA3

Poids moléculaire: 118 kDa

ID gène: 3675

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex