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MGMT anticorps (N-Term)

MGMT Reactivité: Humain, Rat, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263244
  • Antigène Voir toutes MGMT Anticorps
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Épitope
    • 17
    • 12
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 74
    • 18
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 69
    • 12
    Lapin
    Clonalité
    • 61
    • 20
    Polyclonal
    Conjugué
    • 46
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MGMT est non-conjugé
    Application
    • 56
    • 32
    • 21
    • 21
    • 14
    • 12
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    MGMT Antibody detects endogenous levels of total MGMT.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MGMT, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MGMT Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Autre désignation
    MGMT (MGMT Produits)
    Synonymes
    anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt
    Sujet

    Description: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Gene: MGMT

    Poids moléculaire
    22 kDa
    ID gène
    4255
    UniProt
    P16455
    Pathways
    Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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