NCOR2 anticorps (C-Term)

N° du produit ABIN6263545

Cet anticorps anti-NCOR2 Polyclonal Lapin (ABIN6263545) détecte spécifiquement NCOR2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NCOR2 anticorps (C-Term) (ABIN6263545)

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NCOR2 anticorps

Épitope: C-Term

Specificité: NCOR2 Antibody detects endogenous levels of total NCOR2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NCOR2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NCOR2

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Autre désignation: NCOR2

Sujet:

Description: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

Gene: NCOR2

Poids moléculaire: 274 kDa

ID gène: 9612

UniProt: Q9Y618

Pathways: Signalisation Notch, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha